In Vitro Fertilization is the union of the ovule and sperm in the laboratory, outside the mother’s womb. It is applied in cases where artificial insemination has proved ineffective in achieving pregnancy.
Fertilization can occur by conventional IVF or by ICSI (Intracytoplasmic Sperm Injection).
Who is it for?
- Patients in whom simpler previous treatments have failed, such as artificial insemination.
- Women with injuries or absence of fallopian tubes.
- Cases with severe endometriosis.
- Women with insufficient ovocitary quality.
- Repeated failed implantation.
- Couples with low quality semen.
Through gonadotropins subcutaneously. Periodic ultrasound and blood checks are performed to control the maturation of the ovules. The ideal is to achieve maturation of about 8-10 ovules in order to have a good chance of success.
It is performed in the operating room with the sedated patient. The puncture is carried out by transvaginal ultrasound and usually lasts 10-15 minutes. Afterwards, the patient is discharged and a relative rest of 24-48 hours is recommended at home.
It can be done in two ways depending on the case.
- Conventional IVF: each ovule is placed on a culture plate along with several thousand sperm cells and it is expected 24 hours for fertilization to occur.
- ICSI: a technique that involves the injection of a single sperm into the egg, using a micropipette, with the help of a special microscope. Currently some centres already have a new microscope that allows this technique to be performed at many more magnifications, in what is known as IMSI. In this way we can be much more precise in sperm injection.
Embryos obtained from fertilization are grown in special culture media in the IVF laboratory, following a rigorous observation process regarding their morphology and cell number. The culture is prolonged for five or six days, until the embryos reach the blastocyst phase. This offers us more criteria to select embryos with greater implantation potential.
An embryo is inserted into the patient’s uterus through a special cannula. The rest of good quality embryos are vitrified to transfer them in subsequent cycles without the need for ovarian stimulation or puncture.
- Will I be able to lead a normal life during IVF treatment?
During the treatment it is possible to have abdominal discomfort and a feeling of swelling, but the vast majority of patients can continue with their usual life. The only day that it is advised to remain at rest at home would be the day of follicular puncture, since this procedure requires the administration of sedation. The next day it is possible to return to work without any problems whatsoever.
- If IVF is unsuccessful, how long do I have to wait to start a new treatment?
It has not been established that there are any benefits from leaving a period of time between IVF treatments. Thus, once you have your period after a negative beta test, you can start a new IVF treatment or an endometrial preparation for cryotransfer in case you have vitrified embryos (link to cryotransfer)Obviously, before starting a new treatment, patients must have recovered both physically and psychologically, and it must be verified that there are no factors that indicate that we must carry out additional tests before making a new attempt.
- When does implantation occur? What should I do after the transfer?
Embryo implantation must occur within 3 days after embryo transfer, so it is recommended to continue with normal life but avoiding significant efforts especially in these first days. In addition, it is vitally important to continue with the medication schedule indicated by the gynecologist.
he success rates shown correspond to those of our headquarters in Marbella. The percentages presented in this section have been divided as follows:
eta-hCG positive: hormone produced by the body once the embryo is implanted in the uterus. Calculated after 10/12 days after embryo transfer.
Clinical Pregnancy: Calculated in the 5 week gestation by means of ultrasound. Its presence is a sign of implantation of the embryo in the endometrium.
SEF (Spanish Fertility Society). The rates shown here correspond to the last report published by the agency in 2016.